Shigella Infections Market Insights, Epidemiology Facts, and Emerging Therapies 2032
DelveInsight’s “Shigella Infections Market Insights” report delivers an in-depth understanding of the Shigella Infections, historical & forecasted epidemiology, as well as the Shigella Infections Market Trends in the 7MM (the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan) for the study period 2019-2032.
Shigella Infections Overview
Shigellosis is a major global health problem and the main sign of Shigella infection is diarrhea, which often is bloody. In addition to this, symptoms of shigellosis may include fever, as well as stomach pain. Shigellosis occurs for the most part, in developing countries due to overcrowding and poor sanitation. Children’s, non-breastfed infants, children recovering from measles, malnourished children, and adults older than 50 years have a more severe illness and a greater risk of death. Transmission occurs via the fecal-oral route, person-to-person contact, household flies, infected water, and inanimate objects.
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Shigella Infections Epidemiology Insights
Shigella infection is restricted to humans and is predominantly transmitted from person to person through direct or indirect fecal-oral contact. Besides this, the sources of infection include ingestion of contaminated food and drinking or recreational water, and sexual contact (especially among men who have sex with men). Furthermore, the severity of Shigellosis varies by patient age and by infecting species and is characterized by diarrhea, fever, nausea, and cramps.
Some of the key highlights of the Shigella Infections Market Report
- According to the California Department of Public health (US), Shigella causes approximately 450,000 cases of diarrhea in the United States annually. Shigella germs are very contagious and can spread easily from person to person.
- The Laboratory-based Enteric Disease Surveillance (LEDS) system contributes to the understanding of human shigellosis in the United States by collecting reports of infections from state and regional public health laboratories. As per this organization, S. sonnei accounts for the largest percentage of infections followed by S.flexneri, S. boydii and S. dysenteriae.
- As per findings from secondary domain, there is no visible predominance between, males and females case of Shigellosis.
Shigella Infections Epidemiology Segmentation
- Total Shigella Infections Incident Cases
- Shigella Infections Species-specific Incident cases
- Shigella Infections Age-specific Incident cases
- Shigella Infections Treated Pool
Shigella Infections Symptoms
People with shigellosis may experience mild or severe diarrhea (loose stools), often with fever and traces of blood or mucus in the stool. Some infected persons will also experience nausea and vomiting, while others may not show any symptoms at all.
Shigella Infections Diagnosis
Shigellosis is diagnosed by performing laboratory testing on feces. The laboratory can also perform special tests to determine which antibiotics if any, would be best for treating the infection.
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Shigella Infections Market Insights
On a global scale, of millions of Shigella diarrheal episodes are estimated to occur each year. Among those, the majority of cases are observed to be in developing countries, mainly in children. Several complications arise due to Shigellosis which include sepsis, rectal prolapse, arthralgia, intestinal perforation, toxic megacolon, electrolyte imbalance, seizures, and leukemoid reactions. Once infected, all Shigella species multiply and cause acute bloody diarrhea by invading the colonic epithelium where pro-inflammatory cytokines are released, and the subsequent inflammatory reaction destroys the epithelial cells lining the gut mucosa, allowing for further direct invasion by Shigella.
Shigella Infections Treatment Market
“Shigellosis is usually self-limited and treatment with antibiotics is not generally recommended in otherwise healthy adults with mild illness”. However, antibiotics may be prescribed when warranted by the severity of the illness, underlying health conditions. Anti-diarrheal medication that inhibits peristalsis are contraindicated and may prolong illness and increase the rate of complications, therefore not preferred to treat this condition. However, it is noteworthy to mention that Shigellosis is becoming more difficult to treat because of increasing antibiotic resistance.
Shigella Infections Emerging Therapies
- Fluoroquinolones
- Beta-lactams
- Cephalosporins
- GSK4069327A
Shigella Infections Market Dynamics
The dynamics of Shigellosis market is anticipated to change in the coming years owing to the increase in the initiatives towards control of drug-resistance, emergence of new candidates for the management of this situation during the forecast period of 2020–2030. Some of the key players, such as LimmaTech Biologics AG, GlaxoSmithKline, Immuron and others have recently entered in the therapeutic market of Shigellosis at a global level.
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Table of content
1. Key Insights
2. Executive Summary
3. Competitive Intelligence Analysis
4. Market Overview at a Glance
5. Disease Background and Overview
6. Patient Journey
7. Epidemiology and Patient Population
8. Treatment Algorithm, Current Treatment, and Medical Practices
9. Unmet Needs
10. Key Endpoints of Shigella Infections Treatment
11. Marketed Products
12. Emerging Therapies
13. Seven Major Market Analysis
14. Attribute analysis
15. 7MM: Market Outlook
16. Access and Reimbursement Overview
17. KOL Views
18. Market Drivers
19. Market Barriers
20. Appendix
21. DelveInsight Capabilities
22. Disclaimer
23. About DelveInsight
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